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Cortisol, Stress, and Why You Wake at 3am
Sleep Science 5 min read

Cortisol, Stress, and Why You Wake at 3am

Waking up suddenly in the middle of the night isn't just bad luck. It's often a chemical reaction to stress.

The Nocturnal Alarm Clock

It is a common phenomenon: you fall asleep easily, but at 3:00 AM, your eyes snap open. You are wide awake, mind racing. This is rarely a bladder issue; it is usually a blood sugar and cortisol issue.

The Cortisol-Glucose Connection

During the night, your body needs a steady supply of glucose to keep your brain functioning. If your blood sugar drops too low (often due to stress or a poor evening diet), your brain perceives this as an emergency. To mobilize more glucose, the adrenal glands release cortisol and adrenaline.

These are stress hormones. They are designed to wake you up and get you moving. When they spike at 3:00 AM, they pull you out of deep sleep and into a state of alert wakefulness. Because your frontal cortex (logic) is groggy and your amygdala (fear) is active, worries seem magnified and unsolvable.

Stabilizing the Night

Preventing the 3:00 AM wake-up call starts with stabilizing blood sugar and managing stress during the day. Eating a balanced dinner with healthy fats and fiber can prevent nocturnal hypoglycemia. Additionally, reducing circulating cortisol before bed—through breathwork or adaptogens like Reishi—can dampen the adrenal response, helping you stay asleep through the night.